PABPC4 BROADLY INHIBITS CORONAVIRUS REPLICATION BY DEGRADING NUCLEOCAPSID PROTEIN THROUGH SELECTIVE AUTOPHAGY

PABPC4 Broadly Inhibits Coronavirus Replication by Degrading Nucleocapsid Protein through Selective Autophagy

ABSTRACT Emerging coronaviruses (CoVs) can cause severe diseases in humans and animals, and, as of yet, none of the currently available broad-spectrum drugs or vaccines can effectively Merchandising Freezers control these diseases.Host antiviral proteins play an important role in inhibiting viral proliferation.One of the isoforms of cytoplasmic pol

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Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome

BackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a consequence of in-utero exposure to prenatal maternal opioids, resulting in the manifestation of symptoms like irritability, feeding problems, tremors, and withdrawal signs.Opioid use disorder Isolator (OUD) during pregnancy can profoundly impact both mother and fetus, disrupting fetal brain

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Geo-Temporal Selective Approach for Dynamic Depth Estimation in Outdoor Object Detection and Distance Measurement

Accurate depth information is crucial for various computer vision applications such as augmented reality, 3D modeling, and autonomous vehicles.Recent advancements have significantly improved both supervised and self-supervised methods for depth estimation.However, most current approaches primarily focus on monocular depth estimation and face challe

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Intracoronary pharmacological therapy versus aspiration thrombectomy in STEMI (IPAT-STEMI): A systematic review and meta-analysis of randomized trials.

BackgroundThrombus load in STEMI patients remains a challenge in practice.It aggravates coronary obstruction leading to impaired myocardial perfusion, worsened cardiac function, and adverse clinical outcomes.Various strategies have been advocated to reduce thrombus burden.ObjectivesThis meta-analysis aimed to evaluate the effectiveness of intracoro

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